Scott Pautler, MD
Curriculum Vitae

EDUCATION

Undergraduate: University of Florida College of Arts and Sciences Gainesville, FL Degree: Bachelor of Science 9/73 - 3/77

Graduate: University of South Florida College of Medicine Tampa, FL Degree: Doctor of Medicine 7/77 - 6/80

Internship: University of South Carolina Richland Memorial Hospital Columbia, SC General Surgery Internship 7/80 - 6/81

Residency: University of South Florida Tampa, FL Ophthalmology Residency 7/81 - 6/84

Fellowship: Bascom Palmer Eye Institute University of Miami Miami, FL Medical Retina Fellowship J. Donald M. Gass, M.D. 7/84 - 6/85

Bascom Palmer Eye Institute University of Miami Miami, FL Vitreoretinal Surgery Fellowship 7/85 - 6/86

AWARDS AND HONORS

Phi Eta Sigma Honorary University of Florida, 1974

Sigma Tau Sigma Honorary University of Florida, 1975

Epsilon Delta Honorary University of Florida, 1975

Who's Who Among Students in American Colleges and Universities University of Florida, 1977

High Honors Graduate University of Florida, 1977

Outstanding Student Award University of South Florida College of Medicine, 1980

Clinical Diagnosis Award Bascom Palmer Eye Institute University of Miami, 1986

Curtis D. Benton, Jr., M.D. Young Ophthalmologist Leadership Award Florida Society of Ophthalmology, June 6, 1993

Physician's Recognition Award American Medical Association, June 1, 199

8 The Best Doctors in America 1998-2010

Who's Who in Executives and Professionals National Register, 2000

Who's Who in Diabetes Treatment Education And Research American Diabetes Association, 2001

ACADEMIC APPOINTMENTS

Assitant Clinical Professor Department of Ophthalmology University of South Florida College of Medicine Tampa, FL 8/86 - 7/92

Associate Clinical Professor Department of Ophthalmology University of South Florida College of Medicine Tampa, FL 7/92 - 7/2003

Affiliate Associate Professor Department of Ophthalmology University of South Florida College of Medicine Tampa, FL 8/2003 - 7/2010

ADMINISTRATIVE APPOINTMENTS

St Joseph's Hospital Department of Ophthalmology Tampa, FL - Chairman, 7/88 - 12/89

Florida Society of Ophthalmology - Chairman, Diabetes 1990-98, 2000 - Chairman, Public Relations, 1993-94 - Executive Committee, 1993-94

Tampa Bay Ophthalmological Society - Secretary/Treasurer, 1991-92 - Vice-President, 1992-93 - President, 1993-94

American Diabetes Association Florida Affiliate, Inc. - Program Committee, 1992-1995 - Board of Directors, 1992-1995 - Vice-President, 1993-94 - President, 1994-95

CERTIFICATIONS

Diplomate, National Board of Medical Examiners (1981)

Diplomate, American Board of Ophthalmology (1986)

Fellow, American Academy of Ophthalmology (1986)

Fellow, American College of Surgeons (1991)

PROFESSIONAL SOCIETIES

American Medical Association

American Academy of Ophthalmology

American College of Surgeons

Florida Medical Association

Florida Society of Ophthalmology

Hillsborough County Medical Association

Tampa Bay Ophthalmological Society

American Diabetes Association

American Association for Ophthalmic Standardized Echography

International Society of Ophthalmic Ultrasound

International Society of Ocular Trauma

American Society of Retinal Specialists

The Campo Fluorescein Society

Royal Society of Medicine

HOSPITAL AFFILIATIONS

St. Joseph's Hospital (Senior Active)

University Community Hospital (Senior Active)

RESEARCH

Collaborative Ocular Melanoma Study Co-Investigator (1989- Present)

Endophthalmitis Vitrectomy Study Co-Principal Investigator (1989-94)

USF Silicone Oil Study Co-Principal Investigator (1989-94)

Study of Ocular Complications of AIDS (SOCA)

Investigator (1994-2000)

Age-Related Eye Disease Study Investigator (1997-2001)

rhIGF-1 Type I Diabetes Study Physician Investigator (1997-2000)

Complications of AMD Prevention Trial Co-Principal Investigator (1998-2001)

Phase III Safety and Efficacy Study of Vitrase (Hyaluronidase)for Ophthalmic Intravitreal Injections for Clearance of Severe Vitreous Hemorrhage (VIT-02-08961X) Principal Investigator (1999-2001)

Bausch & Lomb Clinical Protocol 415-001 A Multicenter, Randomized, Double-Masked, Controlled Study to Evaluate the Safety and Efficacy of an Intravitreal Fluocinolone Acetonide (0.5 or 2.0 mg) Implant in Patients with Non-Infectious Uveitis Affecting the Posterior Segment of the Eye Investigator (2001-Present)

CUTS Study of Vitrectomy in the Management of Branch Retinal Vein Occlusion Investigator (2000-Present)

The Natural History of Eyes with Basal Laminar Drusen Study Co-Investigator (2001-Present)

Lilly Protein Kinase C Inhibitor Studies: Diabetic Retinopathy Study 2 Co-Investigator (2001-Present)

Multicenter Uveitis Steroid Treatment (MUST) Trial Implant Surgeon (2005-Present)

A Phase III, Multicenter, Randomized, Double-Masked, Active Treatment-Controlled Study of the Efficacy and Safety of rhuFAb V2 (Ranibizumab) Compared with Verteporfin (Visudyne) Photodynamic Therapy in Subjects with Predominately Classic Subfoveal Neovascular Age-related Macular Degeneration (Genentech Inc. & Novartis Parma AG) Sub-investigator (2005 to present)

A Phase III, Multicenter, Randomized, Double-Masked, Sham Injection-Controlled Study of the Efficacy and Safety of rhuFab V2 (Ranibizumab) in Subjects with Minimally Classic or Occult Subfoveal Neovascular Age-related Macular Degeneration (Genentech Inc. & Novartis Pharma AG) Sub-investigator (2005 to present)

A Phase I/II, Single-Masked, Multicenter Study of the Safety, Tolerability, and Efficacy of Multiple-Dose Intravitreal Injections of rhuFab V2 in Combination with Verteporfin (Visudyne) Photodynamic Therapy in Subjects with Neovascular Age-Related Macular Degeneration (Genentech Inc. & Novartis Pharma AG) Sub-investigator (2005 to present)

Protein Kinase C Beta Inhibitor-Diabetic Retinopathy Study Number II (PKC-DRS2) A Phase III Clinical Trial. Protocol Number B7A-MC-MBCM Sub-investigator (2005)

ARTICLES & ABSTRACTS

Pautler SE, Grizzard WS, Thompson LN, Wing GL: Blindness from retrobulbar injection into the optic nerve: its cause, fundus picture, and prevention. Poster Presentation. American Academy of Ophthalmology 1983.Ophthal Surg 1986;17(6):334-337.

Pautler SE, Goldstein BG: Intrastromal iris hemorrhage in a patient with hemoglobin C trait. Ann Ophthalmol 1984;16:945.

Grizzard WS, Blackshear WM, Pautler SE, Lamb S: Use of pulsed Doppler ultrasonography to evaluate blood flow in intraocular melanomas. Presented at DESIDUO meeting in St. Petersburg, FL. November 9, 1984.

Fenske NA, Lober CW, Pautler SE: Congenital bullous urticaria pigmentosa: Treatment with concomitant use of H1 and H2 receptor antagonists. Arch Derm 1985;121:115-118.

Pautler SE, Goldstein BG: Rhegmatogenous retinal detachment with subretinal exudates. Ann Ophthalmol 1985;17:489-493.

Pavan PR, Brinser JH, McLane NJ, Pautler SE: Treatment of endophthalmitis without systemic antibiotics. Presented at Association for Research in Vision and Ophthalmology annual meeting, Sarasota, FL. May 6-10, 1985.

Gass JDM, Pautler SE: Toxemia of pregnancy pigment epitheliopathy masquerading as a heredomacular dystrophy. Trans Am Ophthalmol Soc 1985, 83:114.

Pautler SE: Fleck Retina in Kjellin's Syndrome (letter) Am J Ophthalmol 1985,99:618-619.

Margo CE, Bullington WD, Pautler SE: Occult suprachoroidal hemorrhage and posterior scleral rupture. Am J Ophthalmol 1988, 106:358-359.

Lewis ML, Pautler SE: Retinal pigment epithelial detachments with neovascular membranes in age-related macular degeneration: Natural history versus laser photocoagulation. Published in: Gitter KA, Schatz H, Yannuzzi LA, McDonald HR, eds. Laser Photocoagulation of Retinal Disease. San Francisco: Pacific Medical Press, 1988.

Pautler SE: Inherited retinal venous beading (letter). American Journal of Ophthalmology 1989,107:686.

Gass JDM, Gieser RG, Wilkinson CP, Beahm DE, Pautler SE: Bilateral diffuse uveal melanocytic proliferation in patients with occult carcinoma. Archives of Ophthalmology 1990, 108:527-533.

Margo CE, Pautler SE: Granulomatous uveitis following treatment of choroidal melanoma with proton beam irradiation. Retina 1990,10:140-3.

Doft BH, Barza M. Optimal management of postoperative endophthalmitis and results of the Endophthalmitis Vitrectomy Study. Curr Opin Ophthalmol 1996 June;7(3):84-94.

Han DP, Wisniewski SR, Wilson LA et al. Spectrum and susceptibilities of microbiologic isolates in the Endophthalmitis Vitrectomy Study. Am J Ophthalmol 1996 July;122(1):1-17.

Microbiologic factors and visual outcome in the endophthalmitis vitrectomy study. Am J Ophthalmol 1996 December;122(6):830-46.

Studies of Ocular Complications of AIDS in Collaboration with the AIDSClinical Trials Group: Assessment of cytomegalovirus retinitis: Clinical evaluation versus centralized grading of fundus photographs. Arch Ophthalmol 114: 791-805, 1996.

Studies of Ocular Complications of AIDS in Collaboration with the AIDS Clinical Trials Group: Clinical vs. photographic assessment of treatmentof cytomegalovirus retinitis Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial Report 8. Arch Ophthalmol 114:848-855, 1996.

Studies of Ocular Complications of AIDS in collaboration with the AIDS Clinical Trails Group: Parenteral cidofovir for cytomegalovirus retinitis in patients with AIDS: The HPMPC Peripheral Cytomegalovirus Retinitis Trial. Ann Intern Med. 126:264-274, 1997.

Johnson MW, Doft BH, Kelsey SF et al. The Endophthalmitis Vitrectomy Study. Relationship between clinical presentation and microbiologic spectrum. Ophthalmology 1997 February;104(2):261-72.

Bannerman TL, Rhoden DL, McAllister SK, Miller JM, Wilson LA. The source of coagulase-negative staphylococci in the Endophthalmitis Vitrectomy Study. A comparison of eyelid and intraocular isolates using pulsed-field gel electrophoresis. Arch Ophthalmol 1997 March;115(3):357-61.

Wisniewski SR, Hammer ME, Grizzard WS et al. An investigation of the hospital charges related to the treatment of endophthalmitis in the Endophthalmitis Vitrectomy Study. Ophthalmology 1997 May;104(5):739-45.

Barza M, Pavan PR, Doft BH et al. Evaluation of microbiological diagnostic techniques in postoperative endophthalmitis in the Endophthalmitis Vitrectomy Study. Arch Ophthalmol 1997 September;115(9):1142-50.

Doft BH, Kelsey SF, Wisniewski SR. Additional procedures after the initial vitrectomy or tap-biopsy in the Endophthalmitis Vitrectomy Study. Ophthalmology 1998 April;105(4):707-16.

Ayyala RS, Cruz DA, Margo CE, Harman LE, Pautler SE, Misch DA, Mines JA, and Richards, DW: Cystoid Macular Edema Associated with Latanoprost in Aphakic and Pseudophakic Eyes. Am J Opthalmol 126:602-604, 1998.

Aylward GW, Chang TS, Pautler SE, Gass JDM: A Long Term Follow Up of Choroidal Osteoma. Arch Ophthalmol 116:1337-41, 1998.

Wisniewski SR, Capone A, Kelsey SF, Groer-Fitzgerald S, Lambert HM, Doft BH. Characteristics after cataract extraction or secondary lens implantation among patients screened for the Endophthalmitis Vitrectomy Study. Ophthalmology 2000 July;107(7):1274-82.

Doft BM, Kelsey SF, Wisniewski SR. Retinal detachment in the endophthalmitis vitrectomy study. Arch Ophthalmol 2000 December;118(12):1661-5.

Czajka M, Fekrat S. Vitrase ISTA Pharmaceuticals. IDrugs 2002 April;5(4):356-62.

Hyaluronidase (Vitrase)--ISTA: hyaluronidase--ISTA pharmaceuticals. Drugs R D 2003;4(3):194-7.

Scorolli L, Corazza D, Morara M, Vismara S, Lugaresi ML, Meduri RA. Argon laser vs. subthreshold infrared (810-nm) diode laser macular grid photocoagulation in nonexudative age-related macular degeneration. Can J Ophthalmol 2003 October;38(6):489-95.

Jacobson MA, Maecker HT, Orr PL, D'Amico R, Van Natta M, Li XD, Pollard RB, Bredt BM; Adult AIDS Clinical Trials Group and the Studies of Ocular Complications of AIDS Research Group. Results of a cytomegalovirus (CMV)-specific CD8+/interferon- gamma+ cytokine flow cytometry assay correlate with clinical evidence of protective immunity in patients with AIDS with CMV retinitis. J Infect Dis. 2004 Apr 15; 189 (8): 1362-73. Epub 2004 Mar 31.

Marshall BC, Jacobson MA, Adler SP; Studies of Ocular Complications of AIDS Research Group, Avidity of antibodies to cytomegalovirus in HIV-seropositive patients with and without CMV retinitis. Viral Immunol. 2004; 17 (1): 101-8.

Cohen SM., Pautler SE, Cohen, ML, Fayssal El-Jabali. OCT Findings in Group 2A IJRT-Submitted for Publication

Kuppermann BD, Thomas EL, de S, Grillone LR. Pooled efficacy results from two multinational randomized controlled clinical trials of a single intravitreous injection of highly purified ovine hyaluronidase (Vitrase) for the management of vitreous hemorrhage. Am J Ophthalmol 2005 October;140(4):573-84.

Kuppermann BD, Thomas EL, de S, Grillone LR. Safety results of two phase III trials of an intravitreous injection of highly purified ovine hyaluronidase (Vitrase) for the management of vitreous hemorrhage. Am J Ophthalmol 2005 October;140(4):585-97.

Bhavsar A, Grillone L, McNamara T, Gow J, Hochberg A, Pearson R. Predicting Response Of Vitreous Hemorrhage And Outcome Of Photocoagulation After Intravitreous Injection Of Highly Purified Ovine Hyaluronidase in Patients with Diabetes. Invest Ophthalmol Vis Sci 2008 April 25.

Ying GS, Maguire MG, Liu C, Antoszyk AN. Night Vision Symptoms and Progression of Age-related Macular Degeneration in the Complications of Age-related Macular Degeneration Prevention Trial. Ophthalmology 2008 July 30.

Oliva AM, Pavan PR, Margo CE, Pautler SE. Recalcitrant Candida endophthalmitis associated with mannose-binding lectin deficiency. Arch Ophthalmol 2009 June;127(6):822-3.

Pautler S. Diabetic Macular Ischemia. In: Browning D, editor. Diabetic Retinopathy: Evidence Based Management. Springer; 2010. 203-25.

Pautler S. Treatment of proliferative diabetic retinopathy. In: Browning D, editor. Diabetic Retinopathy: Evidence Based Management. Springer; 2010. 227-304.

Browning D, Pautler S, Telander D, Wong K, Stewart M, Bhavsar A. Clinical Examples in Managing Diabetic Retinopathy. In: Browning D, editor. Diabetic Retinopathy: Evidence Based Management. Springer; 2010. 403-39.

The Multicenter Uveitis Steroid Treatment Trial Research Group: The Multicenter Uveitis Steroid Treatment Trial: Rationale, Design, and Baseline Characteristics. Am J Ophthalmol 2010 April: 149:550-561.

Eichenbaum D, Cohen S, Billiris-Findlay, K.  “Monthly Versus Treat-and-Extend Ranibizumab for Center-Involving Diabetic Macular Edema: a Prospective Randomized Investigator-Sponsored Trial,” Club Vit, July 1, 2014.

Eichenbaum D, Cohen S, Billiris-Findlay, K.  “Monthly Versus Treat-and-Extend Ranibizumab for Center-Involving Diabetic Macular Edema: a Prospective Randomized Investigator-Sponsored Trial,” American Society of Retinal Specialists, August 11, 2014.

Pautler SE, Cohen SM, Findlay KB, Eichenbaum DA, Lopez M. Clinical findings of the posterior uveal effusion syndrome. American Academy of Ophthalmology. 2015 Annual Meeting. Abstract ID 30043320. Poster Presentation PO476