Central Serous Retinopathy

Central serous retinopathy causes central vision loss secondary to fluid leaking under the center of the macula.

What is a Central Serous Retinopathy?

Moderate central vision loss in men (90% of these cases are men) aged 40 to 60 is sometimes caused by central serous retinopathy. Central serous retinopathy is caused by excessively leaky blood vessels in the choroid which is the layer of blood vessels under the retina. When these vessels become excessively leaky, fluid builds up in the choroid and some of that fluid can break through the barrier of the retinal pigment epithelium. The retinal pigment epithelium is a single layer of cells under that retina that are water tight. The fluid that breaks through the retinal pigment epithelium builds up under the retina forming a blister of fluid under the retina. This fluid blurs the vision in two ways. First, because the retina is elevated away from the retinal pigment epithelium by the fluid, it does not receive nutrients and oxygen as efficiently as it should and it doesn't work well. Second, because the retina is not where it should be, images become out of focus. Some people with central serous retinopathy will notice if they wear reading glasses, they can see better because the reading glasses can sometimes refocus the image on the elevated retina.

Cause of Central Serous Retinopathy

The animated image shows a classic smokestack on fluorescein angiography in a patient with acute central serous retinopathy. The white trace dye, fluorescein, does not leak out of the pigment epithelium under the retina. In patients with central serous retinopathy, there is leakage in the choroid of fluid that builds up and then pushes through the barrier layer under the retina, the retina pigment epithelium. That shows up as a leaky spot on the fluorescein angiogram. Because of the concentration gradient in the subretinal fluid, the fluorescein dye moves up from the leaky spot and forms a smokestack looking white are under the center of the macula.

Central Serous Retinopathy and Fundus Autofluorescence

There are several tests that can be done to establish the diagnosis of central serous retinopathy and to help guide management. Fundus autofluorescence - in the accompanying photograph, show the area of bright autofluorescence from the serous retinal detachment. The photoreceptor outer segments that accumulate in the serous retinal detachment autofluoresce and show up bright in the image. Also optical coherence tomography can show the choroidal thickening and the subretinal fluid. Fluorescein angiography and indocyaning green angiography will show which areas of the choroid are leaking and can help guide treatment.

Who develops Central Serous Retinopathy

Central serous retinopathy is associated with Type A personality. Ninety percent of cases occur in men. It is also sometimes seen in people taking steroids orally or by nasal spray. It can also be associated with pregnancy. Serous retinal detachments like those seen in central serous retinopathy can also seen in patients with severe high blood pressure, age related macular degeneration, and posterior uveitis.

The diagnosis of central serous retinopathy is usually established with optical coherence tomography, fluorescein angiography, and sometimes indocyanine green angiography.

Visual acuity usually returns to normal within about 6 months (sometimes sooner) in 95 percent of affected patients. The recurrence rate is 25 percent. If vision does not recover in a reasonably amount of time, hot laser, photodynamic therapy (cold laser) can be considered.

What is Chronic Central Serous Retinopathy

There are some patient who develop chronic central serous retinopathy. Those patients have subretinal fluid for more than 6 months. Sometimes subretinal fluid will persist for years. In those situations, the chronic subretinal fluid causes damage to the pigment epithelium and the overlying retina. Vision loss gradually develops. When a patient is treated for chronic subretinal fluid, even when the fluid goes away, there is often residual vision loss. Sometimes, with treatment, the vision loss can be stabilized or slowed. The accompanying image shows gutters where the chronic subretinal fluid tracks down due to gravity and causes damage that is visible with testing.

Central Serous Retinopathy Treatment

Very few patients with central serous retinopathy require treatment. 90% of patients improve without therapy. Sometimes, central serous retinopathy becomes chronic and causes vision loss that does not improve. Focal laser treatment to the leaking spot is usually effective in patients with CSR. More commonly, photodynamic laser with visudyne is used to treat CSR. Photodynamic laser is a very low power laser which is used to activate the visudyne. The visudyne is infused intravenously over 10 minutes then a 5 minute washout period is observed. Then 86 seconds of laser (low enegery) is used to activate the the drug and seal up the leaky areas in the choroid. This treatment is usually effective. It is likely safer than focal laser but does sometimes need to be repeated.

Central Serous Retinopathy NEWS

Below are current articles from a Google News Feed on Central Serous Retinopathy

Clinical spectrum of severe chronic central serous chorioretinopathy a | OPTH  Dove Medical Press

Clinical spectrum of severe chronic central serous chorioretinopathy and outcome of photodynamic therapy Danial Mohabati,1,2 Elon HC van Dijk,1 Thomas J ...

Central serous retinopathy and hand-foot-mouth disease: coincidence or | IMCRJ  Dove Medical Press

Central serous retinopathy and hand-foot-mouth disease: coincidence or causation? Selina Taylor,1 Maureen Khan,2 Shams Zaidi,3 Umair Alvi,4 Yaqoot ...

Predictors of Outcome During Eplerenone Therapy in Chronic Central Serous Chorioretinopathy:A Prospective, Open-Label Pilot Clinical Study  Healio

Ophthalmic Surgery, Lasers and Imaging Retina | BACKGROUND AND OBJECTIVE:To assess the treatment response and predictive factors following ...

$1.12 Bn Optical Coherence Tomography (OCT) Market - Global Outlook & Forecasts 2017-2026  PRNewswire

DUBLIN, Feb. 7, 2019 /PRNewswire/ -- The "Optical Coherence Tomography (OCT) - Global Market Outlook (2017-2026)" report has been added to...

Clinical characteristics and long-term visual outcome of severe phenot | OPTH  Dove Medical Press

Clinical characteristics and long-term visual outcome of severe phenotypes of chronic central serous chorioretinopathy Danial Mohabati,1,2 Thomas J van ...

India- Optical Coherence Tomography Market Report to Grow at a CAGR of 11.7% by 2024 with Analysis by Type, Technology, Application, Size, Share, Growth Rate, End-User, Geography  MENAFN.COM

(MENAFN - GetNews) Global Optical Coherence Tomography Market, By Type (Catheter Based OCT Device, Doppler OCT Devices, Handheld OCT Devices, ...

Patients respond differently to central serous retinopathy treatment  Healio

WASHINGTON – A multitude of management options exist for central serous retinopathy, and “if the patient doesn't become better in 3 to 4 months, consider ...

Long-term outcomes in half-dose verteporfin photodynamic therapy for c | OPTH  Dove Medical Press

Long-term outcomes in half-dose verteporfin photodynamic therapy for chronic central serous retinopathy Nadeem Ali Dhirani,1 Yelin Yang,2 Sohel Somani2–4 ...

Characteristics of the Choriocapillaris Layer in Optical Coherence Tomography Angiography of Acute Central Serous Chorioretinopathy  Healio

Ophthalmic Surgery, Lasers and Imaging Retina | BACKGROUND AND OBJECTIVE:To describe the vascular characteristics of the choriocapillaris layer in acute ...

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Central Serous Chorioretinopathy: Risk Factors Identified  Medscape

H pylori infection, steroid use, disturbed sleep, autoimmune disease, psychopharmacologic medication use, and type A behavior were among possible risk ...

PDT should be considered for chronic central serous chorioretinopathy  Healio

WAILEA, Hawaii — Retina specialists should consider photodynamic therapy as an adjunctive treatment for chronic central serous chorioretinopathy, according ...

Half-dose verteporfin PDT increases visual acuity, reduces recurrence in central serous chorioretinopathy  Healio

COLORADO SPRINGS, Colo. — Photodynamic therapy with half-dose verteporfin significantly increased visual acuity in eyes with central serous ...

Optical Coherence Tomography Market 2024 Analysis and Global Growth by Top Key Manufacturers Johnson & Johnson, Roche, Essilor, Axsun Technologies, Topcon Medical Systems, Avinger Inc., Agfa HealthCare, Carl Zeiss Meditec AG, Heidelberg Engineering  openPR

The report Global Optical Coherence Tomography Market, By Type (Catheter Based OCT Device, Doppler OCT Devices, Handheld OCT Devices, Tabletop OCT ...

Array BioPharma Reports Financial Results for the Second Quarter of Fiscal 2019  PRNewswire

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Treating Central Serous Retinopathy: Adjunctive Nutritional Management  Dynamic Chiropractic

Central serous retinopathy (CSR), or central serous chorioretinopathy (CSC), is an eye disease that causes visual impairment. The condition is often temporary, ...

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NSAIDs Speed Central Serous Choroidopathy Recovery  Medscape

NEW ORLEANS — Patients with central serous choroidopathy treated with nonsteroidal anti-inflammatory drug (NSAID) eyedrops recover faster than when they ...

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New treatment avenue to prevent serious retinal detachment  Science Daily

Wet age-related macular degeneration (AMD) is the leading cause of severe vision loss in older individuals. AMD and other serious chronic eye problems that ...

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Elderly man has central vision loss, lipofuscin accumulation  Healio

Primary Care Optometry News | A 74-year-old Caucasian man presented with a chief complaint of bilateral and symmetric progressive decrease in central vision ...

Spotlight on fundus autofluorescence | OPTO  Dove Medical Press

Spotlight on fundus autofluorescence Ana M Calvo-Maroto,1 Alejandro Cerviño2 1Department of Ophthalmology, Clínica Universidad de Navarra, University of ...

1-year results of combined half-dose photodynamic therapy and ranibizumab for polypoidal choroidal vasculopathy  BMC Blogs Network

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Prevalence and causes of blindness, visual impairment, and cataract su | OPTH  Dove Medical Press

Prevalence and causes of blindness, visual impairment, and cataract surgery in Timor-Leste Marcelino Correia,1 Taraprasad Das,2,3 Julia Magno,1 Bernadette ...

Optometry's Meeting by the American Optometric Association (AOA) 2017  Medscape

Optometry's Meeting by the American Optometric Association (AOA) : Read clinically focused news coverage of key developments from AOA 2017.

More Ways To Wreck Your Eyes Without Even Thinking About It  Motherboard

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According to a phase II study, over 40% of patients with metastatic or unresectable urothelial carcinoma responded to treatment with erdafitinib.

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My Hospital Eye or: How I Started to Love iPhoneography  PetaPixel

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Janssen Plans Year-End Erdafitinib Filing Based on Phase II Data in FGFR-Mutated Bladder Cancer  GenomeWeb

NEW YORK (GenomeWeb) – Janssen will pursue US marketing approval for the FGFR inhibitor erdafitinib after a Phase II study showed the drug shrunk tumors ...

High-tech 3D optical test free at BMC Eye Center  Manila Bulletin

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Women bosses who say the secret of their success comes from napping on the job  Daily Mail

Manchester bosses Fran Elkinson, 49, and Tally Bookbinder, 45 revealed how their 20 to 40 minutes nap during the work day has enabled them to continue to ...

Omega-3 Fatty Acids Protect Eyes Against Retinopathy, Study Finds  National Institutes of Health (press release)

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8 Secrets Your Eyes Reveal About Your Health!  PsychCentral.com

Eight things your eyes reveal about your health gives you 8 solid facts on eye health and your emotional and physical wellness. Do you know these 8 secrets?

Dave Harold has quit snooker because of an eye condition | Daily Star  Daily Star

SNOOKER star Dave Harold has quit the sport because of an eye condition which means he can hardly see the table.

Lessons for the Practicing Ophthalmologist  Medscape

You won't want to miss these highlights of clinical eye research from Wills Eye Hospital.

Zeiss introduces Veracity Surgical platform  Healio

NEW ORLEANS — Carl Zeiss Meditec introduced the Veracity Surgical platform, a cloud-based, intuitive cataract surgery planning program, during a company ...

New chemical composition of 'poppers' linked to retinal damage: Harms associated with these recreational drugs should be reassessed, urge researchers  Science Daily

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Young, pregnant woman complains of 'smudge' in vision  Healio

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Young woman reports blurry vision in one eye, spots, floaters  Healio

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New iterations of laser trabeculoplasty emerging for glaucoma treatment  Healio

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Laser treatment of eyes that have developed drug tolerance to anti-VEGF inhibitors restores drug sensitivity safely and effectively in patients with AMD.

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New England College of Optometry (NECO) students, faculty, alumni, professional staff, and residents delivered presentations, posters, research, and lectures ...

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Ocular Surgery News | An 18-year-old woman presented to our clinic with a complaint of 3 days of decreased vision in her right eye. She reported that the vision ...

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